The objective of the theoretical/practical “Kinetics2025” course is to illustrate the large diversity of biophysical methods that have been developed over the years for the determination of rates of association (kon) and dissociation (koff) in a variety of contexts, and to provide an invaluable opportunity to assess hands-on the strong points of a number of commercially available instruments.
The course will cover different techniques such as:
Surface-based methods: SPR, BLI, GCI, SwitchSense, QCM,…
Real-time cell-binding assays
In-solution methods: stopped-flow, FIDA, kinetic ITC
Single molecule/particle methods: AFM, magnetic tweezers, mass photometry
Time will also be dedicated to data analysis and FAIR database deposition.
Other details: The course is aimed at scientists with experience in at least one method of kinetic characterization of biomolecular interactions, who wish to deepen their knowledge of the field and acquire new scientific and technical skills. Applicants can be graduate or PhD students, postdoctoral fellows, technicians or engineers, early career or more senior researchers, working in whatever academic or industrial context. The applicants should show that the outcome of the course will be used directly in their projects and activities.
Registration to the course will be free of charge. Daily lunches and coffee breaks will be provided to all participants. Candidates can also apply for travel bursaries of up to €500 upon proof of expenses (reimbursed after the course).
Visit the website to find out more and to apply to take part in the school.
https://www.mosbri.eu/training/advanced-level-schools/als2/