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Welcome to the P4EU Network

The P4EU (Protein Production and Purification Partnership in Europe) is a professional network, whose members engage in various aspects of protein expression, purification and characterization in academic settings such as universities or research institutes, typically core technology platforms.

The P4EU was conceived in 2010 with the initial kick-off meeting in Halle, Germany in February 2011. Since then, at least one 2-day meeting has been hosted each year by member’s institutes, which has led the P4EU across Europe and allowed visits to individual platforms, thereby allowing exchange of ideas on set-ups. Currently, we have more than 150 members of the P4EU with a meeting attendance of 30-40 P4EU protein experts plus an equivalent number of local attendees. In addition to meetings, there is a very active on-line discussion forum ensuring that trusted, expert advice is never further away than the fingertips.
The mission of P4EU is to create a forum for informal exchange of experiences and solutions to common problems to avoid “re-invention of the wheel” in parallel. This could relate to, amongst other subjects

  • Evaluation of and hands-on experience with new technologies
  • Identification of sources of expertise
  • Generating awareness of reagents available to the wider community
  • Benchmarking and standard operation procedures – “How does my platform perform relative to others – and how can this be optimised ?” – initiative here include:
  • Establishing standards for protein quality control (joint effort with the ARBRE biophysics network)
  • Comparing baculovirus and mammal expression protocols
  • On-going benchmarking of the PROSS algorithm for optimising protein stability
  • Crowd-funding initiatives to pool resources e.g. sequencing the Sf21 genome

Taken together, the P4EU facilitates contacts between like-minded scientists in an open atmosphere with the meetings being highly stimulating events with high-quality talks as rich sources of inspiration.

Projects and Benchmarks

PROSS Benchmarking
Insect and HEK benchmarking
Sf21 genome assembly

Courses

International Post-graduate Course on Protein Quality Control, University of Siena, June 24 to 27, 2025
Advanced Level School-Biophysical methods for the real-time characterization of biomolecular interactions (Kinetics 2025) 31st March – 4th April 2025, Institut Pasteur (Pasteur-PFBMI), Paris, France.

Upcoming P4EU Meetings

The 21st P4EU Meeting, Universities of Lund and Gothenburg, Gothenburg, 25th-27th August 2025.

Upcoming Conferences

Public Forum

Place to leave your comments to your work or discuss important topics.

Contact

Place to leave your comments to your work or discuss important topics.

Wiki

You can find useful information about the Protein technologies here and share your knowledge.

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